The female genital tract microbiota Composition, relation to innate immune factors, and effects of contraceptives
نویسنده
چکیده
................................................................................ ......5 Publications...................................................................................7 List of abbreviations................................................................................................8 Introduction........................................................................... .......9 The female lower genital tract Anatomy.........................................................................10 Histology..........................................................................11 Composition of the vaginal secretion.................................... ...13 Defence systems of the lower FGT..........................................13 Membrane associated factors................................................15 Cytokines and chemokines....................................................16 Antimicrobial peptides/proteins (AMPs)....................................17 Infections of the lower FGT...............................................................17 Bacterial Vaginosis BV-associated complications.................................................20 Treatment of BV................................................................21 Diagnostic methods............................................................21 The vaginal microbiota The normal vaginal microbiota..............................................23 BV-associated bacteria........................................................26 Factors influencing the vaginal microbiota................................26 Aims of the study...........................................................................29 Material and methods.....................................................................30 Results and Discussion.....................................................................38 Conclusion....................................................................................53 Acknowledgements.........................................................................54 References....................................................................................56 Paper I-IV....................................................................................69
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